diff --git a/drivers/ieee802154/ieee802154_nrf5.c b/drivers/ieee802154/ieee802154_nrf5.c
index 56b1c57f8e..1036c56f03 100644
--- a/drivers/ieee802154/ieee802154_nrf5.c
+++ b/drivers/ieee802154/ieee802154_nrf5.c
@@ -23,6 +23,7 @@ LOG_MODULE_REGISTER(LOG_MODULE_NAME);
 #include <debug/stack.h>
 
 #include <soc.h>
+#include <soc_secure.h>
 #include <device.h>
 #include <init.h>
 #include <debug/stack.h>
@@ -69,16 +70,14 @@ static struct nrf5_802154_data nrf5_data;
 
 #if defined(CONFIG_IEEE802154_NRF5_UICR_EUI64_ENABLE)
 #if defined(CONFIG_SOC_NRF5340_CPUAPP)
+#if defined(CONFIG_TRUSTED_EXECUTION_NONSECURE)
+#error "NRF_UICR->OTP is not supported to read from non-secure"
+#else
 #define EUI64_ADDR (NRF_UICR->OTP)
+#endif /* CONFIG_TRUSTED_EXECUTION_NONSECURE */
 #else
 #define EUI64_ADDR (NRF_UICR->CUSTOMER)
 #endif /* CONFIG_SOC_NRF5340_CPUAPP */
-#else
-#if defined(CONFIG_SOC_NRF5340_CPUAPP) || defined(CONFIG_SOC_NRF5340_CPUNET)
-#define EUI64_ADDR (NRF_FICR->INFO.DEVICEID)
-#else
-#define EUI64_ADDR (NRF_FICR->DEVICEID)
-#endif /* CONFIG_SOC_NRF5340_CPUAPP || CONFIG_SOC_NRF5340_CPUNET */
 #endif /* CONFIG_IEEE802154_NRF5_UICR_EUI64_ENABLE */
 
 #if defined(CONFIG_IEEE802154_NRF5_UICR_EUI64_ENABLE)
@@ -108,15 +107,17 @@ static void nrf5_get_eui64(uint8_t *mac)
 	uint32_t index = 0;
 
 #if !defined(CONFIG_IEEE802154_NRF5_UICR_EUI64_ENABLE)
+	uint32_t deviceid[2];
+
 	/* Set the MAC Address Block Larger (MA-L) formerly called OUI. */
 	mac[index++] = (IEEE802154_NRF5_VENDOR_OUI >> 16) & 0xff;
 	mac[index++] = (IEEE802154_NRF5_VENDOR_OUI >> 8) & 0xff;
 	mac[index++] = IEEE802154_NRF5_VENDOR_OUI & 0xff;
-#endif
 
-#if defined(CONFIG_SOC_NRF5340_CPUAPP) && \
-	defined(CONFIG_TRUSTED_EXECUTION_NONSECURE)
-#error Accessing EUI64 on the non-secure mode is not supported at the moment
+	soc_secure_read_deviceid(deviceid);
+
+	factoryAddress = (uint64_t)deviceid[EUI64_ADDR_HIGH] << 32;
+	factoryAddress |= deviceid[EUI64_ADDR_LOW];
 #else
 	/* Use device identifier assigned during the production. */
 	factoryAddress = (uint64_t)EUI64_ADDR[EUI64_ADDR_HIGH] << 32;