diff --git a/arch/posix/CMakeLists.txt b/arch/posix/CMakeLists.txt
index 907fb5dd9e..d50437de7a 100644
--- a/arch/posix/CMakeLists.txt
+++ b/arch/posix/CMakeLists.txt
@@ -104,7 +104,7 @@ elseif (CONFIG_NATIVE_LIBRARY)
     # no_builtin to avoid the compiler using builtin replacements for std library functions
     zephyr_compile_options(
       -nostdinc
-      -isystem ${COMPILER_OWN_INCLUDE_PATH}
+      #-isystem ${COMPILER_OWN_INCLUDE_PATH}
       "SHELL:-include ${ZEPHYR_BASE}/arch/posix/include/undef_system_defines.h"
       $<TARGET_PROPERTY:compiler,freestanding>
       $<TARGET_PROPERTY:compiler,no_builtin>
diff --git a/lib/libc/newlib/CMakeLists.txt b/lib/libc/newlib/CMakeLists.txt
index 35c6a9b633..336b1cd86d 100644
--- a/lib/libc/newlib/CMakeLists.txt
+++ b/lib/libc/newlib/CMakeLists.txt
@@ -4,7 +4,7 @@ zephyr_library()
 zephyr_library_sources(libc-hooks.c)
 
 # Do not allow LTO when compiling libc-hooks.c file
-set_source_files_properties(libc-hooks.c PROPERTIES COMPILE_OPTIONS $<TARGET_PROPERTY:compiler,prohibit_lto>)
+set_source_files_properties(libc-hooks.c PROPERTIES COMPILE_OPTIONS $<TARGET_PROPERTY:compiler,prohibit_lto>;$<TARGET_PROPERTY:compiler,prohibit_cfi>)
 
 # Zephyr normally uses -ffreestanding, which with current GNU toolchains
 # means that the flag macros used by newlib 3.x <inttypes.h> to signal
diff --git a/lib/libc/picolibc/CMakeLists.txt b/lib/libc/picolibc/CMakeLists.txt
index 87fb0d9d8e..4540a6a421 100644
--- a/lib/libc/picolibc/CMakeLists.txt
+++ b/lib/libc/picolibc/CMakeLists.txt
@@ -4,7 +4,7 @@ zephyr_library()
 zephyr_library_sources(libc-hooks.c)
 
 # Do not allow LTO when compiling libc-hooks.c file
-set_source_files_properties(libc-hooks.c PROPERTIES COMPILE_OPTIONS $<TARGET_PROPERTY:compiler,prohibit_lto>)
+set_source_files_properties(libc-hooks.c PROPERTIES COMPILE_OPTIONS "$<TARGET_PROPERTY:compiler,prohibit_lto>;$<TARGET_PROPERTY:compiler,prohibit_cfi>")
 
 # define __LINUX_ERRNO_EXTENSIONS__ so we get errno defines like -ESHUTDOWN
 # used by the network stack