diff --git a/boards/arm/sam4e_xpro/sam4e_xpro-pinctrl.dtsi b/boards/arm/sam4e_xpro/sam4e_xpro-pinctrl.dtsi
index 749b794667..e83b9eeffe 100644
--- a/boards/arm/sam4e_xpro/sam4e_xpro-pinctrl.dtsi
+++ b/boards/arm/sam4e_xpro/sam4e_xpro-pinctrl.dtsi
@@ -6,6 +6,19 @@
 #include <dt-bindings/pinctrl/sam4eXe-pinctrl.h>
 
 &pinctrl {
+	afec0_default: afec0_default {
+		group1 {
+			pinmux = <PA17X_AFEC0_AD0>,
+				 <PC13X_AFEC0_AD6>;
+		};
+	};
+	afec1_default: afec1_default {
+		group1 {
+			pinmux = <PB2X_AFEC1_AD0>,
+				 <PB3X_AFEC1_AD1>;
+		};
+	};
+
 	gmac_mii: gmac_mii {
 		group1 {
 			pinmux = <PD0A_GMAC_GTXCK>,
diff --git a/boards/arm/sam4e_xpro/sam4e_xpro.dts b/boards/arm/sam4e_xpro/sam4e_xpro.dts
index c42b1934af..24bcfc7f4a 100644
--- a/boards/arm/sam4e_xpro/sam4e_xpro.dts
+++ b/boards/arm/sam4e_xpro/sam4e_xpro.dts
@@ -126,6 +126,20 @@
 	clock-frequency = <120000000>;
 };
 
+&afec0 {
+	status = "okay";
+
+	pinctrl-0 = <&afec0_default>;
+	pinctrl-names = "default";
+};
+
+&afec1 {
+	status = "okay";
+
+	pinctrl-0 = <&afec1_default>;
+	pinctrl-names = "default";
+};
+
 &twi0 {
 	status = "okay";
 
diff --git a/drivers/adc/adc_sam_afec.c b/drivers/adc/adc_sam_afec.c
index dce5044544..167122d845 100644
--- a/drivers/adc/adc_sam_afec.c
+++ b/drivers/adc/adc_sam_afec.c
@@ -1,6 +1,7 @@
 /*
  * Copyright (c) 2017 comsuisse AG
  * Copyright (c) 2018 Justin Watson
+ * Copyright (c) 2023 Gerson Fernando Budke
  *
  * SPDX-License-Identifier: Apache-2.0
  */
@@ -33,8 +34,10 @@
 LOG_MODULE_REGISTER(adc_sam_afec);
 
 #define NUM_CHANNELS 12
-
 #define CONF_ADC_PRESCALER ((SOC_ATMEL_SAM_MCK_FREQ_HZ / 15000000) - 1)
+#ifndef AFEC_MR_ONE
+#define AFEC_MR_ONE AFEC_MR_ANACH
+#endif
 
 typedef void (*cfg_func_t)(const struct device *dev);
 
@@ -106,11 +109,13 @@ static int adc_sam_channel_setup(const struct device *dev,
 		return -EINVAL;
 	}
 
+#ifdef AFEC_11147
 	/* Set single ended channels to unsigned and differential channels
 	 * to signed conversions.
 	 */
 	afec->AFEC_EMR &= ~(AFEC_EMR_SIGNMODE(
 			  AFEC_EMR_SIGNMODE_SE_UNSG_DF_SIGN_Val));
+#endif
 
 	return 0;
 }
@@ -284,9 +289,12 @@ static int adc_sam_init(const struct device *dev)
 	}
 
 	/* Enable PGA and Current Bias. */
-	afec->AFEC_ACR = AFEC_ACR_PGA0EN
+	afec->AFEC_ACR = AFEC_ACR_IBCTL(1)
+#ifdef AFEC_11147
+		       | AFEC_ACR_PGA0EN
 		       | AFEC_ACR_PGA1EN
-		       | AFEC_ACR_IBCTL(1);
+#endif
+		       ;
 
 	/* Enable AFEC clock in PMC */
 	(void)clock_control_on(SAM_DT_PMC_CONTROLLER,
diff --git a/dts/arm/atmel/sam4e.dtsi b/dts/arm/atmel/sam4e.dtsi
index 38f8f3f182..98e8fe583e 100644
--- a/dts/arm/atmel/sam4e.dtsi
+++ b/dts/arm/atmel/sam4e.dtsi
@@ -50,6 +50,24 @@
 			compatible = "mmio-sram";
 		};
 
+		afec0: adc@400b0000 {
+			compatible = "atmel,sam-afec";
+			reg = <0x400b0000 0x4000>;
+			interrupts = <30 0>;
+			clocks = <&pmc PMC_TYPE_PERIPHERAL 30>;
+			status = "disabled";
+			#io-channel-cells = <1>;
+		};
+
+		afec1: adc@400b4000 {
+			compatible = "atmel,sam-afec";
+			reg = <0x400b4000 0x4000>;
+			interrupts = <31 0>;
+			clocks = <&pmc PMC_TYPE_PERIPHERAL 31>;
+			status = "disabled";
+			#io-channel-cells = <1>;
+		};
+
 		eefc: flash-controller@400e0a00 {
 			compatible = "atmel,sam-flash-controller";
 			reg = <0x400e0a00 0x200>;
diff --git a/samples/drivers/adc/boards/sam4e_xpro.overlay b/samples/drivers/adc/boards/sam4e_xpro.overlay
new file mode 100644
index 0000000000..f83fec237c
--- /dev/null
+++ b/samples/drivers/adc/boards/sam4e_xpro.overlay
@@ -0,0 +1,35 @@
+/*
+ * SPDX-License-Identifier: Apache-2.0
+ *
+ * Copyright (c) 2023, Gerson Fernando Budke
+ */
+
+#include <zephyr/dt-bindings/adc/adc.h>
+
+/ {
+	zephyr,user {
+		/* adjust channel number according to pinmux in board.dts */
+		io-channels = <&afec0 0>, <&afec0 6>;
+	};
+};
+
+&afec0 {
+	#address-cells = <1>;
+	#size-cells = <0>;
+
+	channel@0 {
+		reg = <0>;
+		zephyr,gain = "ADC_GAIN_1";
+		zephyr,reference = "ADC_REF_INTERNAL";
+		zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
+		zephyr,resolution = <12>;
+	};
+
+	channel@6 {
+		reg = <6>;
+		zephyr,gain = "ADC_GAIN_1";
+		zephyr,reference = "ADC_REF_INTERNAL";
+		zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
+		zephyr,resolution = <12>;
+	};
+};